Compound register
Cognitive · IndiaCommercial Supply

Bacopa

Bacopa monnieri

Bacoside-standardised whole-plant extract from Indian Ayurvedic supply chains. Memory and neuroprotective research base.

Bacosides A+B ≥ 20% (HPLC)GMP-alignedPer-batch COA
≥20%BACOSIDES
A+B
20:1DER
STANDARD
80MESH
US STD
36 moSHELF
LIFE

Botanical reference

Bacopa monnieri.

Family
Plantaginaceae
Plant part
Whole plant (aerial)
Origin
India

Overview

Bacopa (Bacopa monnieri (L.) Wettst.) is a small perennial herb of the Plantaginaceae family, native to the wetlands of the Indian subcontinent. Motark sources Bacopa whole-plant aerial material from established Ayurvedic supply chains in Kerala and Tamil Nadu, with primary processing colocated at origin.

Extraction is performed in GMP-aligned facilities through hydroalcoholic processes optimised for bacoside recovery. Total bacosides (A and B series) are characterised by HPLC against a reference standard, with a standard release specification of ≥ 20% w/w. Higher-spec tiers (≥ 40%, ≥ 50%) are available against the formulation brief.

Traditional use

Bacopa monnieri — known traditionally as Brahmi — has a continuous documented history of use in Indian Ayurvedic preparations. The aerial parts of the plant are typically prepared as decoctions, infusions, or oil-based macerations, with classical Ayurvedic texts documenting its use in nervine and rasayana formulations.

Motark's compound monograph documents the traditional context as cultural background only. No therapeutic claims are made and no dosage guidance is provided through this site — these are matters for licensed practitioners and the regulatory frameworks of the markets in which finished products are sold.

Modern research

The principal characterised constituents of Bacopa monnieri are the bacosides — a family of triterpenoid saponins including bacoside A (a mixture of bacoside A3, bacopaside II, bacopaside X, and bacopasaponin C) together with bacoside B. Bacosides A and B form the conventional standardisation target; Motark's release specification is ≥ 20% w/w by HPLC.

Published peer-reviewed work spans phytochemistry, analytical method development, and clinical pharmacokinetics. Citations available on request from the team.

Specifications

Release spec.

Standard commercial specification below. Higher-spec tiers and custom standardisations available against the formulation brief.

Botanical name
Bacopa monnieri (L.) Wettst.
Family
Plantaginaceae
Plant part
Whole plant (aerial)
Extraction solvent
Hydroalcoholic (50% EtOH)
Extraction ratio (DER)
20:1 standard
Standardisation marker
Bacosides A + B (HPLC)
Specification
≥ 20% w/w bacosides A+B (≥ 40%, ≥ 50% available)
Appearance
Light brown powder
Particle size
80 mesh (US standard)
Loss on drying
≤ 5.0%
Heavy metals
Pb < 0.5 ppm · As < 1.0 ppm · Cd < 0.3 ppm · Hg < 0.1 ppm
Microbial
TPC < 1,000 CFU/g · Y&M < 100 CFU/g · E. coli absent in 1 g
Pesticide residues
Compliant with USP <565>, EU MRLs

Markers and supply

Active markers and packaging.

Active markers

  • Bacosides A + B

    ≥ 20% w/w (≥ 40%, ≥ 50% available)

    Method: HPLC

  • Bacoside A3 · bacopaside II · bacopaside X · bacopasaponin C

    Individually profiled per batch

    Method: HPLC

  • Total triterpenoid saponins

    ≥ 55%

    Method: Gravimetric

Packaging

Bulk powder
1 kg · 5 kg · 25 kg fibre drums (food-grade liner, vacuum-sealed)
Custom packaging
Available on request for OEM partners

Storage

Store in a cool, dry place away from direct sunlight. Keep container tightly closed and protected from moisture.

Shelf life: 36 months from date of manufacture when stored sealed under specified conditions

Structure · 2DCID 920431832D chemical structure of Bacosides A+BBacosides A+B

Structure & references

Bacosides A+B.

The release marker for Bacopa is Bacosides A+B, quantified by hplc against a reference standard at a specification of ≥ 20%.

PubChem record

CID 92043183

Structural data, IUPAC name, SMILES, and physicochemical properties mirrored from the canonical record at the US National Library of Medicine.

Regulatory status

Status by market.

Regulatory framework summary for the markets covered as standard. Additional jurisdictions and custom dossier work routed through the regulatory team.

Market
Status
Notes
United States
Dietary ingredient
European Union
Permitted food ingredient
Australia
Listed-medicine ingredient
Hong Kong
Permitted ingredient
ASEAN
Traditional ingredient
Per harmonised ASEAN traditional medicine framework

Applications

Common uses.

  • Capsule and tablet supplements for memory, focus, and cognition
  • Nootropic stacks and cognitive-support blends
  • Traditional Ayurvedic preparations (including ghee-based formats)
  • Liquid extract and tincture formulations
  • Custom-spec extract supply for OEM and contract manufacturers

Documentation pack

Standard deliverables.

  • Certificate of Analysis (COA) — per batch, retained 7 yearsPer batch
  • Specification sheetPer batch
  • Heavy metals reportPer batch
  • Pesticide residue reportPer batch
  • Microbial testing reportPer batch
  • Stability dataPer batch
  • Country of origin certificatePer batch
  • Material Safety Data SheetPer batch

For procurement and formulation

Sample, quote, or full dossier.

Request a representative sample with the standard intake pack, pricing for your specified spec tier and annual volume, or the full regulatory dossier on request from the team.